L101V (p.Leu101Val) variant of CRBN (Protein cereblon)
L101V (p.Leu101Val) in CRBN (Protein cereblon) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
L101V (p.Leu101Val) variant details
- p.Leu101Val
- TOPMed rs1285884277
- Missense
- Variant Prioritization Score for Impact Estimate 0.471
- REVEL 0.24
- CADD 26.00
- PolyPhen-2 0.99
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 2.2e-05)
- Structural context available