K116N (p.Lys116Asn) variant of CRBN (Protein cereblon)
K116N (p.Lys116Asn) in CRBN (Protein cereblon) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
K116N (p.Lys116Asn) variant details
- p.Lys116Asn
- ESP rs145695200
- ExAC rs145695200
- gnomAD rs145695200
- Missense
- Variant Prioritization Score for Impact Estimate 0.212
- REVEL 0.13
- CADD 17.00
- PolyPhen-2 0.03
- SIFT 0.30
- Most common in the HGDP:BANTUSOUTHAFRICA population (allele frequency 0.19)
- Structural context available