I81T (p.Ile81Thr) variant of CRBN (Protein cereblon)
I81T (p.Ile81Thr) in CRBN (Protein cereblon) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
I81T (p.Ile81Thr) variant details
- p.Ile81Thr
- Ensembl rs1707737789
- Missense
- Variant Prioritization Score for Impact Estimate 0.6
- REVEL 0.58
- CADD 26.30
- PolyPhen-2 0.58
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 0.0006)
- Structural context available