G5R (p.Gly5Arg) variant of CRBN (Protein cereblon)
G5R (p.Gly5Arg) in CRBN (Protein cereblon) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
G5R (p.Gly5Arg) variant details
- p.Gly5Arg
- TOPMed rs1250225494
- gnomAD rs1250225494
- Missense
- Variant Prioritization Score for Impact Estimate 0.219
- REVEL 0.12
- CADD 23.50
- PolyPhen-2 0.00
- SIFT 0.01
- Most common in the HGDP:YAKUT population (allele frequency 0.8)
- Structural context available