G5E (p.Gly5Glu) variant of CRBN (Protein cereblon)
G5E (p.Gly5Glu) in CRBN (Protein cereblon) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
G5E (p.Gly5Glu) variant details
- p.Gly5Glu
- 1000Genomes rs143087756
- ESP rs143087756
- ExAC rs143087756
- TOPMed rs143087756
- Missense
- Variant Prioritization Score for Impact Estimate 0.163
- REVEL 0.15
- CADD 15.80
- PolyPhen-2 0.00
- SIFT 0.12
- Most common in the HGDP:BIAKA population (allele frequency 0.091)
- Structural context available