F67Y (p.Phe67Tyr) variant of CRBN (Protein cereblon)
F67Y (p.Phe67Tyr) in CRBN (Protein cereblon) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
F67Y (p.Phe67Tyr) variant details
- p.Phe67Tyr
- TOPMed rs1707739692
- Missense
- Variant Prioritization Score for Impact Estimate 0.327
- REVEL 0.20
- CADD 22.30
- PolyPhen-2 0.11
- SIFT 0.19
- Most common in the 1KG:PJL population (allele frequency 0.0052)
- Structural context available