E32V (p.Glu32Val) variant of CRBN (Protein cereblon)
E32V (p.Glu32Val) in CRBN (Protein cereblon) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
E32V (p.Glu32Val) variant details
- p.Glu32Val
- gnomAD rs1405796444
- Missense
- Variant Prioritization Score for Impact Estimate 0.439
- REVEL 0.28
- CADD 28.00
- PolyPhen-2 0.98
- SIFT 0.05
- Most common in the Latino/Admixed American population (allele frequency 0.0018)
- Structural context available