D9A (p.Asp9Ala) variant of CRBN (Protein cereblon)
D9A (p.Asp9Ala) in CRBN (Protein cereblon) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
D9A (p.Asp9Ala) variant details
- p.Asp9Ala
- ESP rs148285043
- ExAC rs148285043
- TOPMed rs148285043
- gnomAD rs148285043
- Missense
- Variant Prioritization Score for Impact Estimate 0.171
- REVEL 0.02
- CADD 24.30
- PolyPhen-2 0.04
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 0.00028)
- Structural context available