D6G (p.Asp6Gly) variant of CRBN (Protein cereblon)
D6G (p.Asp6Gly) in CRBN (Protein cereblon) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
D6G (p.Asp6Gly) variant details
- p.Asp6Gly
- TOPMed rs908451988
- gnomAD rs908451988
- Missense
- Variant Prioritization Score for Impact Estimate 0.207
- REVEL 0.09
- CADD 22.60
- PolyPhen-2 0.00
- SIFT 0.42
- Most common in the REMAINING population (allele frequency 5e-05)
- Structural context available