D35N (p.Asp35Asn) variant of CRBN (Protein cereblon)
D35N (p.Asp35Asn) in CRBN (Protein cereblon) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
D35N (p.Asp35Asn) variant details
- p.Asp35Asn
- ExAC rs780239031
- TOPMed rs780239031
- gnomAD rs780239031
- Missense
- Variant Prioritization Score for Impact Estimate 0.417
- REVEL 0.17
- CADD 24.20
- PolyPhen-2 0.26
- SIFT 0.03
- Most common in the HGDP:BANTUSOUTHAFRICA population (allele frequency 0.19)
- Structural context available