A62T (p.Ala62Thr) variant of CRBN (Protein cereblon)
A62T (p.Ala62Thr) in CRBN (Protein cereblon) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
A62T (p.Ala62Thr) variant details
- p.Ala62Thr
- TOPMed rs928255811
- gnomAD rs928255811
- Missense
- Variant Prioritization Score for Impact Estimate 0.0929
- REVEL 0.03
- CADD 7.57
- PolyPhen-2 0.00
- SIFT 0.26
- Most common in the HGDP:BANTUSOUTHAFRICA population (allele frequency 0.19)
- Structural context available