A11V (p.Ala11Val) variant of CRBN (Protein cereblon)
A11V (p.Ala11Val) in CRBN (Protein cereblon) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
A11V (p.Ala11Val) variant details
- p.Ala11Val
- gnomAD rs866123640
- Missense
- Variant Prioritization Score for Impact Estimate 0.18
- REVEL 0.05
- CADD 22.60
- PolyPhen-2 0.00
- SIFT 0.30
- Most common in the HGDP:BIAKA population (allele frequency 0.068)
- Structural context available