A11G (p.Ala11Gly) variant of CRBN (Protein cereblon)
A11G (p.Ala11Gly) in CRBN (Protein cereblon) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
A11G (p.Ala11Gly) variant details
- p.Ala11Gly
- gnomAD rs866123640
- Missense
- Variant Prioritization Score for Impact Estimate 0.177
- REVEL 0.04
- CADD 22.50
- PolyPhen-2 0.01
- SIFT 0.39
- Most common in the Ashkenazi Jewish population (allele frequency 0.0037)
- Structural context available