S49L (p.Ser49Leu) variant of CRB1 (Protein crumbs homolog 1)
S49L (p.Ser49Leu) in CRB1 (Protein crumbs homolog 1) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The record also includes variant effect predictions and structural context.
S49L (p.Ser49Leu) variant details
- p.Ser49Leu
- NCI-TCGA Cosmic COSV6634
- cosmic curated COSV66343
- Variant assessed as somatic; moderate impact.
- Missense
- MetaLR 0.42
- MetaSVM -0.56
- SIFT 0.46
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available