S25Y (p.Ser25Tyr) variant of CRB1 (Protein crumbs homolog 1)
S25Y (p.Ser25Tyr) in CRB1 (Protein crumbs homolog 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data, published literature, and structural context.
S25Y (p.Ser25Tyr) variant details
- p.Ser25Tyr
- gnomAD 1-197328425-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.566
- REVEL 0.63
- MetaLR 0.74
- MetaSVM 0.56
- CADD 22.50
- PolyPhen-2 0.67
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available