C85F (p.Cys85Phe) variant of CRB1 (Protein crumbs homolog 1)

C85F (p.Cys85Phe) in CRB1 (Protein crumbs homolog 1) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of Retinitis pigmentosa 12; Leber congenital amaurosis 8. The record also includes published literature and structural context.

C85F (p.Cys85Phe) variant details