C67R (p.Cys67Arg) variant of CRB1 (Protein crumbs homolog 1)
C67R (p.Cys67Arg) in CRB1 (Protein crumbs homolog 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
C67R (p.Cys67Arg) variant details
- p.Cys67Arg
- Ensembl rs1571847873
- Missense
- Variant Prioritization Score for Impact Estimate 0.663
- REVEL 0.74
- MetaLR 0.95
- MetaSVM 1.10
- CADD 24.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available