T1969A (p.Thr1969Ala) variant of CR1 (Complement receptor type 1)

Name: CR1 T1969A (p.Thr1969Ala) variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-08-21
License: https://catvariant.com/terms-of-use

T1969A (p.Thr1969Ala) in CR1 (Complement receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes published literature.

T1969A (p.Thr1969Ala) variant details

p.Thr1969Ala
rs2296160
UniProt VAR 055686
Missense
Variant Prioritization Score for Impact Estimate 0.256
AlphaMissense 0.08
MetaLR 0.00
MetaSVM -1.01
PolyPhen-2 0.00
SIFT 0.99
Cited in: Ramp Sequence May Explain Synonymous Variant Association with Alzheimer's Disease in the Paired Immunoglobulin-like… (PMID 40149715)
Cited in: Ramp sequence may explain synonymous variant association with Alzheimer's disease in the Paired Immunoglobulin-like… (PMID 39829933)