S1610T (p.Ser1610Thr) variant of CR1 (Complement receptor type 1)
S1610T (p.Ser1610Thr) in CR1 (Complement receptor type 1) is a missense change. Clinical records from EBI and UniProt describe it as benign in the context of in Sl(3) antigen. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes published literature and structural context.
S1610T (p.Ser1610Thr) variant details
- p.Ser1610Thr
- rs4844609
- UniProt VAR 013823
- Benign
- in Sl(3) antigen
- Missense
- Variant Prioritization Score for Impact Estimate 0.335
- AlphaMissense 0.07
- MetaLR 0.20
- MetaSVM -0.89
- PolyPhen-2 0.00
- SIFT 0.34
- MutPred 0.55
- EBI: Benign (in Sl(3) antigen)
- UniProt: Benign (in Sl(3) antigen)
- Structural context available
- Cited in: Complement receptor type 1 and 2 (CR1 and CR2) gene polymorphisms and plasma protein levels are associated with the… (PMID 37833411)
- Cited in: Analysis of the Putative Role of CR1 in Alzheimer's Disease: Genetic Association, Expression and Function. (PMID 26914463)