P6L (p.Pro6Leu) variant of CR1 (Complement receptor type 1)
P6L (p.Pro6Leu) in CR1 (Complement receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
P6L (p.Pro6Leu) variant details
- p.Pro6Leu
- gnomAD 1-207496284-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.113
- REVEL 0.03
- MetaLR 0.05
- MetaSVM -1.03
- CADD 15.80
- PolyPhen-2 0.01
- SIFT 0.19
- Population evidence available
- Structural context available
- Literature evidence available