P14L (p.Pro14Leu) variant of CR1 (Complement receptor type 1)
P14L (p.Pro14Leu) in CR1 (Complement receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
P14L (p.Pro14Leu) variant details
- p.Pro14Leu
- gnomAD 1-207496308-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.135
- REVEL 0.04
- MetaLR 0.03
- MetaSVM -1.03
- CADD 15.30
- PolyPhen-2 0.12
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available