P11A (p.Pro11Ala) variant of CR1 (Complement receptor type 1)
P11A (p.Pro11Ala) in CR1 (Complement receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
P11A (p.Pro11Ala) variant details
- p.Pro11Ala
- rs781322624
- gnomAD 1-207496298-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.262
- REVEL 0.05
- MetaLR 0.06
- MetaSVM -1.08
- CADD 17.50
- PolyPhen-2 0.57
- SIFT 0.10
- Population evidence available
- Structural context available
- Literature evidence available