H1208R (p.His1208Arg) variant of CR1 (Complement receptor type 1)

Name: CR1 H1208R (p.His1208Arg) variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-08-21
License: https://catvariant.com/terms-of-use

H1208R (p.His1208Arg) in CR1 (Complement receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes published literature.

H1208R (p.His1208Arg) variant details

p.His1208Arg
rs2274567
UniProt VAR 013819
Missense
Variant Prioritization Score for Impact Estimate 0.257
AlphaMissense 0.11
MetaLR 0.00
MetaSVM -1.07
PolyPhen-2 0.15
SIFT 0.90
Cited in: Genetic and Epigenetic Dysregulation of CR1 is Associated with Catastrophic Antiphospholipid Syndrome (CAPS). (PMID 40385421)
Cited in: Complement receptor type 1 and 2 (CR1 and CR2) gene polymorphisms and plasma protein levels are associated with the… (PMID 37833411)