F21L (p.Phe21Leu) variant of CR1 (Complement receptor type 1)
F21L (p.Phe21Leu) in CR1 (Complement receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
F21L (p.Phe21Leu) variant details
- p.Phe21Leu
- rs1423387453
- gnomAD 1-207496330-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.165
- REVEL 0.02
- MetaLR 0.03
- MetaSVM -1.03
- CADD 16.40
- PolyPhen-2 0.05
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available