C22R (p.Cys22Arg) variant of CR1 (Complement receptor type 1)
C22R (p.Cys22Arg) in CR1 (Complement receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data, published literature, and structural context.
C22R (p.Cys22Arg) variant details
- p.Cys22Arg
- rs1186041714
- gnomAD 1-207496331-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.0748
- REVEL 0.03
- MetaLR 0.04
- MetaSVM -1.03
- CADD 2.78
- PolyPhen-2 0.00
- SIFT 0.21
- Population evidence available
- Structural context available
- Literature evidence available