W31* (p.Trp31Ter) variant of COMT (Catechol O-methyltransferase)
W31* (p.Trp31Ter) in COMT (Catechol O-methyltransferase) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
W31* (p.Trp31Ter) variant details
- p.Trp31Ter
- TOPMed rs931653147
- gnomAD rs931653147
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.396
- CADD 33.00
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available