W29L (p.Trp29Leu) variant of COMT (Catechol O-methyltransferase)
W29L (p.Trp29Leu) in COMT (Catechol O-methyltransferase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
W29L (p.Trp29Leu) variant details
- p.Trp29Leu
- gnomAD 22-19962612-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.152
- REVEL 0.14
- MetaLR 0.10
- MetaSVM -1.02
- CADD 6.97
- PolyPhen-2 0.00
- SIFT 0.69
- Population evidence available
- Structural context available
- Literature evidence available