P5T (p.Pro5Thr) variant of COMT (Catechol O-methyltransferase)
P5T (p.Pro5Thr) in COMT (Catechol O-methyltransferase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
P5T (p.Pro5Thr) variant details
- p.Pro5Thr
- gnomAD 22-19962539-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.15
- REVEL 0.06
- MetaLR 0.07
- MetaSVM -1.00
- CADD 0.23
- PolyPhen-2 0.01
- SIFT 0.49
- Population evidence available
- Structural context available
- Literature evidence available