P2T (p.Pro2Thr) variant of COMT (Catechol O-methyltransferase)
P2T (p.Pro2Thr) in COMT (Catechol O-methyltransferase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
P2T (p.Pro2Thr) variant details
- p.Pro2Thr
- gnomAD 22-19962530-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.187
- REVEL 0.02
- MetaLR 0.12
- MetaSVM -1.06
- CADD 18.30
- PolyPhen-2 0.00
- SIFT 0.12
- Population evidence available
- Structural context available
- Literature evidence available