P2P (p.Pro2Pro) variant of COMT (Catechol O-methyltransferase)
P2P (p.Pro2Pro) in COMT (Catechol O-methyltransferase) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
P2P (p.Pro2Pro) variant details
- p.Pro2Pro
- rs368616155
- gnomAD 22-19962532-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.118
- CADD 5.32
- Most common in the REMAINING population (allele frequency 4.8e-05)
- Structural context available
- Literature evidence available