N61S (p.Asn61Ser) variant of COMT (Catechol O-methyltransferase)
N61S (p.Asn61Ser) in COMT (Catechol O-methyltransferase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
N61S (p.Asn61Ser) variant details
- p.Asn61Ser
- gnomAD 22-19962708-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0924
- REVEL 0.06
- MetaLR 0.13
- MetaSVM -1.01
- CADD 0.14
- PolyPhen-2 0.00
- SIFT 0.44
- Population evidence available
- Structural context available
- Literature evidence available