N61K (p.Asn61Lys) variant of COMT (Catechol O-methyltransferase)
N61K (p.Asn61Lys) in COMT (Catechol O-methyltransferase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
N61K (p.Asn61Lys) variant details
- p.Asn61Lys
- gnomAD 22-19962709-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.0839
- REVEL 0.04
- MetaLR 0.09
- MetaSVM -1.04
- CADD 0.01
- PolyPhen-2 0.00
- SIFT 0.83
- Population evidence available
- Structural context available
- Literature evidence available