L49L (p.Leu49Leu) variant of COMT (Catechol O-methyltransferase)
L49L (p.Leu49Leu) in COMT (Catechol O-methyltransferase) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data, published literature, and structural context.
L49L (p.Leu49Leu) variant details
- p.Leu49Leu
- gnomAD 22-19962671-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.634
- CADD 7.61
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available