L26L (p.Leu26Leu) variant of COMT (Catechol O-methyltransferase)
L26L (p.Leu26Leu) in COMT (Catechol O-methyltransferase) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
L26L (p.Leu26Leu) variant details
- p.Leu26Leu
- rs756235784
- gnomAD 22-19962602-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0964
- CADD 2.23
- Most common in the East Asian population (allele frequency 2.6e-05)
- Structural context available
- Literature evidence available