L22L (p.Leu22Leu) variant of COMT (Catechol O-methyltransferase)
L22L (p.Leu22Leu) in COMT (Catechol O-methyltransferase) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
L22L (p.Leu22Leu) variant details
- p.Leu22Leu
- gnomAD 22-19962592-G-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.313
- CADD 1.21
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available