H62Y (p.His62Tyr) variant of COMT (Catechol O-methyltransferase)
H62Y (p.His62Tyr) in COMT (Catechol O-methyltransferase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
H62Y (p.His62Tyr) variant details
- p.His62Tyr
- TOPMed rs1942223864
- gnomAD rs1942223864
- Missense
- Variant Prioritization Score for Impact Estimate 0.0729
- REVEL 0.07
- CADD 0.01
- PolyPhen-2 0.00
- SIFT 0.86
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available