G37S (p.Gly37Ser) variant of COMT (Catechol O-methyltransferase)
G37S (p.Gly37Ser) in COMT (Catechol O-methyltransferase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
G37S (p.Gly37Ser) variant details
- p.Gly37Ser
- ExAC rs770700364
- TOPMed rs770700364
- gnomAD rs770700364
- Missense
- Variant Prioritization Score for Impact Estimate 0.0833
- REVEL 0.10
- CADD 0.00
- PolyPhen-2 0.02
- SIFT 0.40
- Most common in the East Asian population (allele frequency 2.6e-05)
- Structural context available