G37R (p.Gly37Arg) variant of COMT (Catechol O-methyltransferase)
G37R (p.Gly37Arg) in COMT (Catechol O-methyltransferase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
G37R (p.Gly37Arg) variant details
- p.Gly37Arg
- ExAC rs770700364
- TOPMed rs770700364
- gnomAD rs770700364
- Missense
- Variant Prioritization Score for Impact Estimate 0.165
- REVEL 0.24
- CADD 0.00
- PolyPhen-2 0.15
- SIFT 0.35
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available