G32V (p.Gly32Val) variant of COMT (Catechol O-methyltransferase)
G32V (p.Gly32Val) in COMT (Catechol O-methyltransferase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
G32V (p.Gly32Val) variant details
- p.Gly32Val
- gnomAD 22-19962621-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.195
- REVEL 0.18
- MetaLR 0.28
- MetaSVM -0.77
- CADD 11.50
- PolyPhen-2 0.45
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available