G32S (p.Gly32Ser) variant of COMT (Catechol O-methyltransferase)
G32S (p.Gly32Ser) in COMT (Catechol O-methyltransferase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
G32S (p.Gly32Ser) variant details
- p.Gly32Ser
- 1000Genomes rs138628382
- ESP rs138628382
- ExAC rs138628382
- TOPMed rs138628382
- Missense
- Variant Prioritization Score for Impact Estimate 0.101
- REVEL 0.06
- CADD 13.30
- PolyPhen-2 0.04
- SIFT 0.15
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available