G32R (p.Gly32Arg) variant of COMT (Catechol O-methyltransferase)
G32R (p.Gly32Arg) in COMT (Catechol O-methyltransferase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
G32R (p.Gly32Arg) variant details
- p.Gly32Arg
- 1000Genomes rs138628382
- ESP rs138628382
- ExAC rs138628382
- TOPMed rs138628382
- Missense
- Variant Prioritization Score for Impact Estimate 0.189
- REVEL 0.19
- CADD 17.30
- PolyPhen-2 0.07
- SIFT 0.02
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available