G32A (p.Gly32Ala) variant of COMT (Catechol O-methyltransferase)
G32A (p.Gly32Ala) in COMT (Catechol O-methyltransferase) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
G32A (p.Gly32Ala) variant details
- p.Gly32Ala
- gnomAD 22-19962617-TG-T
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.19
- CADD 15.40
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available