G15V (p.Gly15Val) variant of COMT (Catechol O-methyltransferase)
G15V (p.Gly15Val) in COMT (Catechol O-methyltransferase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
G15V (p.Gly15Val) variant details
- p.Gly15Val
- cosmic curated COSV52889
- Missense
- Variant Prioritization Score for Impact Estimate 0.228
- REVEL 0.19
- CADD 16.70
- PolyPhen-2 0.21
- SIFT 0.25
- Population evidence available
- Structural context available