G15D (p.Gly15Asp) variant of COMT (Catechol O-methyltransferase)
G15D (p.Gly15Asp) in COMT (Catechol O-methyltransferase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
G15D (p.Gly15Asp) variant details
- p.Gly15Asp
- gnomAD 22-19962570-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.38
- REVEL 0.42
- MetaLR 0.36
- MetaSVM -0.41
- CADD 21.70
- PolyPhen-2 0.82
- SIFT 0.10
- Population evidence available
- Structural context available
- Literature evidence available