A10V (p.Ala10Val) variant of COMT (Catechol O-methyltransferase)
A10V (p.Ala10Val) in COMT (Catechol O-methyltransferase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data and structural context.
A10V (p.Ala10Val) variant details
- p.Ala10Val
- TOPMed rs1457049406
- Missense
- Variant Prioritization Score for Impact Estimate 0.0532
- REVEL 0.05
- CADD 0.85
- PolyPhen-2 0.01
- SIFT 0.25
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available