V85M (p.Val85Met) variant of COMP (P49747)
V85M (p.Val85Met) in COMP (P49747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
V85M (p.Val85Met) variant details
- p.Val85Met
- 1000Genomes rs558270243
- gnomAD rs558270243
- Missense
- Variant Prioritization Score for Impact Estimate 0.222
- REVEL 0.15
- ESM-1b 0.11
- AlphaMissense 0.10
- CADD 18.90
- PolyPhen-2 0.01
- SIFT 0.16
- Most common in the 1KG:GWD population (allele frequency 0.0044)
- Structural context available