S84R (p.Ser84Arg) variant of COMP (P49747)
S84R (p.Ser84Arg) in COMP (P49747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
S84R (p.Ser84Arg) variant details
- p.Ser84Arg
- TOPMed rs2055201141
- Missense
- Variant Prioritization Score for Impact Estimate 0.2
- REVEL 0.22
- ESM-1b 0.00
- AlphaMissense 0.19
- CADD 15.70
- PolyPhen-2 0.07
- SIFT 0.41
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available