P98S (p.Pro98Ser) variant of COMP (P49747)
P98S (p.Pro98Ser) in COMP (P49747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
P98S (p.Pro98Ser) variant details
- p.Pro98Ser
- TOPMed rs905315224
- gnomAD rs905315224
- Missense
- Variant Prioritization Score for Impact Estimate 0.252
- REVEL 0.10
- ESM-1b 0.00
- AlphaMissense 0.09
- CADD 20.90
- PolyPhen-2 0.01
- SIFT 0.29
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available