P32S (p.Pro32Ser) variant of COMP (P49747)
P32S (p.Pro32Ser) in COMP (P49747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
P32S (p.Pro32Ser) variant details
- p.Pro32Ser
- TOPMed rs2055208845
- gnomAD rs2055208845
- Missense
- Variant Prioritization Score for Impact Estimate 0.265
- REVEL 0.07
- ESM-1b 0.00
- AlphaMissense 0.08
- CADD 21.70
- PolyPhen-2 0.23
- SIFT 0.50
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available