P155S (p.Pro155Ser) variant of COMP (P49747)
P155S (p.Pro155Ser) in COMP (P49747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data and structural context.
P155S (p.Pro155Ser) variant details
- p.Pro155Ser
- Ensembl rs2055192540
- Missense
- Variant Prioritization Score for Impact Estimate 0.722
- REVEL 0.63
- ESM-1b 1.00
- AlphaMissense 0.55
- CADD 29.60
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.6e-05)
- Structural context available